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Polynucleotides Explained

Polynucleotides are the latest innovation in regenerative aesthetics, offering a completely different approach to skin rejuvenation. Rather than simply hydrating or filling the skin, polynucleotides stimulate your skin’s natural healing and repair processes at a cellular level.

Derived from highly purified DNA fragments (usually sourced from salmon), polynucleotides work by encouraging tissue regeneration, collagen synthesis, and deep skin repair – making them perfect for restoring skin quality, tone, and texture.


How Do Polynucleotides Work?

Polynucleotides are injected into the skin where they act like a biostimulator – waking up sluggish fibroblasts, improving microcirculation, and promoting skin cell renewal. They also have anti-inflammatory and antioxidant properties, which make them ideal for stressed, tired, or damaged skin.

At Lianne Powell Aesthetics, we use premium polynucleotide products that are backed by clinical research for safety and efficacy.


Benefits of Polynucleotide Treatments

  • Cellular regeneration: Encourages the skin to repair itself from within
  • Improves elasticity and firmness
  • Smooths fine lines and crepey skin
  • Brightens dull, uneven tone
  • Reduces inflammation and redness (ideal for acne-prone or sensitive skin)
  • Minimises dark circles and under-eye hollowing
  • Can also reduce scarring and support skin recovery post-procedure

Results build gradually over time for a natural, refreshed look.


Who are Polynucleotides Good For?

Polynucleotides are incredibly versatile and suitable for a wide range of clients:

Anyone noticing early signs of ageing – loss of firmness, tone, or skin density

Clients with sensitive or compromised skin

Those with acne scars or post-inflammatory pigmentation

Under-eye concerns like dark circles, thinning skin, or fine lines

People seeking a regenerative treatment without adding volume

They’re especially popular for younger clients as a collagen-preserving option, and older clients seeking restorative, non-volumising rejuvenation.


Treatment Plan & Aftercare

  • Usually a course of 3 sessions, 2–4 weeks apart
  • Maintenance every 4–6 months
  • Minor swelling, redness or light bruising may occur
  • Avoid alcohol, saunas, and exercise for 24 hours
  • Stick to gentle skincare and apply SPF daily

Results are progressive and long-lasting, with visible improvements continuing for several weeks post-treatment.


Clinical Information

• Polynucleotides are biocompatible and safe, with minimal risk of allergy

• Administered via microinjections or cannula depending on area

• Commonly used on the face, neck, décolletage, under-eyes, and even for hair restoration

• Not suitable for: pregnancy, breastfeeding, active infections, or known fish allergies


Why Choose Polynucleotides?

This isn’t just skin boosting – it’s skin healing. Polynucleotides are a new frontier in aesthetics, helping your skin to rebuild and strengthen itself naturally. Perfect for clients who want results that are gentle, natural, and rooted in regenerative science.

Book your consultation at Lianne Powell Aesthetics and discover the power of regenerative skin therapy with polynucleotides.